Chapter
30.
Glomerular pathologies and their associated diseases
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Keypoints
- Minimal change nephropathy causes childhood nephrotic syndrome and has
a good prognosis.
- Focal segmental glomerulosclerosis has a poor prognosis and is associated
with HIV infection.
- Membranous nephropathy is a common cause of nephrotic syndrome in the
elderly and is associated with malignancies
- Mesangiocapillary glomerulonephritis is rare and has a poor prognosis.
- IgA nephropathy is common and can cause recurrent frank haematuria.
- Henoch Schonlein purpura causes hematuria, abdominal pain and a rash,
usually in children.
- Diffuse proliferative glomerulonephritis occurs following streptococcal
or other infections and has a good prognosis.
- Crescentic glomerulonephritis represents substantial renal damage and
is can be superimposed on other patterns of glomerular disease or associated
with systemic disorders such as vasculitis.
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