Chapter
23.
Regulation of divalent cations and disorders of phosphate and magnesium
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Keypoints
- Parathyroid hormone (PTH) is a peptide hormone.
- Parathyroid hormone is released by the parathyroid gland in response
to a fall in ionised calcium.
- Parathyroid hormone promotes renal reabsorption of calcium and renal
excretion of phosphate.
- It also promotes vitamin D synthesis and bone resorption.
- Vitamin D is finally metabolised in the kidney.
- Vitamin D promotes calcium and phosphate reabsorption in the kidney
and absorption in the gut and release from bone.
- The major cause of hyperphosphatemia is renal failure.
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